The Clinical Profile of Sumatriptan: Cluster Headache

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The clinical profile of sumatriptan: cluster headache.

Cluster headache is a rare form of severe idiopathic headache characterized by unilateral short-lasting episodes of excruciating pain in association with autonomic disturbances. Subcutaneous sumatriptan has been investigated as an acute treatment for cluster headache in two randomized, double-blind, placebo-controlled, crossover trials. About 75% of patients given subcutaneous sumatriptan 6 mg ...

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Sumatriptan in excessive doses over 15 years in a patient with chronic cluster headache.

We report the case of a 49-year-old lady with cluster headache, who had received sumatriptan s.c. treatment for 15 years with daily dosages between 12 and 222 mg (average of 150 mg during the last year). The therapy was successful in aborting CH attacks. Long-term overdosage of sumatriptan was well tolerated, without adverse events.

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Cluster headache in women: clinical characteristics and comparison with cluster headache in men.

OBJECTIVE To study the clinical characteristics of cluster headache in women. Cluster headache is a disorder of men (male to female ratio 6-7:1). METHODS Retrospective chart review to identify all women diagnosed with cluster headache at an academic headache centre from January 1995 through July 1998. RESULTS Thirty two women and 69 men were identified. The mean age of onset of cluster head...

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Metoclopramide versus sumatriptan for treatment of migraine headache: A randomized clinical trial

BACKGROUND There are different options to manage benign headache in the emergency department. The costs, side effects, and efficacies of the drugs used are significantly different. The aim of this study was to compare intravenous (IV) metoclopramide with subcutaneous (SC) sumatriptan in treatment of migraine headache. MATERIAL AND METHODS In a randomized, double-blinded clinical trial study, ...

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Open label study of intranasal sumatriptan (Imigran) for footballer's headache.

OBJECTIVE To study the efficacy and practicality of treating headache in professional footballers with intranasal sumatriptan. METHODS An open label drug trial was performed in elite Australian footballers using intranasal sumatriptan (20 mg) treatment for acute headache. The main outcome measures were treatment response at 30 minutes, two hours, and 24 hours using two criteria: (a) initial s...

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ژورنال

عنوان ژورنال: European Neurology

سال: 1994

ISSN: 0014-3022,1421-9913

DOI: 10.1159/000119530